Professor Nuran Kumbaraci

ASSOCIATE PROFESSOR, CHEMICAL BIOLOGY
School: Schaefer School of Engineering & Science
Department: Chemistry and Chemical Biology
Building: McLean Chemical Sciences Building
Room: 417
Phone: 201.216.5554
Fax: 201.216.8240
Email: nkumbara@stevens.edu
Education
  • Post-Doctoral Research: Columbia University, New York, New York, College of Physicians and Surgeons, Neurophysiology and Cellular Biophysics
  • Ph.D., M.Phil., M.A., Physiology, College of Physicians and Surgeons, Columbia University, New York, New York
  • M.S., Chemical Engineering, Columbia University, New York, New York
  • B.S., Chemistry, Robert College, Istanbul, Turkey
Research
  • Apply chemical and biochemical methods to determine the mechanism of diseases and develop biomarkers for their early detection.
  • Neuromuscular physiology, biochemistry and biophysics of muscle contraction and synaptic transmission, immunochemical pathways and physiological responses.
General Information

Dr. N. M. Kumbaraci joined the Department of Chemistry and Chemical Engineering at Stevens in 1979 as Assistant Professor to teach and develop the Biology Program.  She designed and taught all the biology courses and the teaching laboratories and established the Chemical Biology program.  She was instrumental in the negotiations between Stevens and UMDNJ-NJMS to start the first Accelerated B.S.-M.D. Combined Degree program in New Jersey.  She is the advisor of the Accelerated Chemical Biology Program.  Over 300 students entered medical, dental, veterinary and health profession schools since then.  Prior to joining Stevens, she worked several years in the pharmaceutical industry in Europe and the US as an R&D and analytical chemist and obtained several patents in liquid, suspension and aerosol formulations.  She then joined the Artificial Organs Research Laboratory at Columbia University conducting research in developing non-thrombogenic synthetic polymers for in vivo and ex vivo applications.  During her pre and post-doctoral studies at the medical school of Columbia University, she taught biology, organic chemistry and physiology at NYU and Barnard/Columbia College.    

 

Experience
  • Stevens Institute of Technology, Associate Professor, 1979-present
  • Barnard/Columbia College and NYU, Organic Chemistry, Biology Instructor
  • Artificial Organs Research Laboratory, Columbia University, New York, NY
  • Lever Brothers Headquarters, New York, NY, Pharmaceutical Marketing
  • Siemens und Halske, Germany, Electrodeposition Laboratory
  • Eczacibasi Pharmaceutical Co., Analytical Research and Product Development Chemist
         *Patents on Aerosol and Liquid Pharmaceutical Products
  • Institutional Service

    HPAC-Health Professions Advisory Committee:  Chairman: 1979-2003; Member: 2003-2016; 2016-Present, co-Chair

    IACUC-Institutional Animal Care and Use Committee, Member

    Biosafety Committee, 1998-2008, Member

    AED-National Health Preprofessional Honor Society, NJ Beta Chapter, Founder and Faculty Advisor, 1992-present

    SHPC-Stevens Health Professions Club, Founder and Faculty Advisor, 1984-present

    SSBS-Stevens Society for Biological Studies, Faculty Advisor, 1979-1984

    Undergraduate Academic Standards and Undergraduate Promotions Committees

    Committee on Committees

     

    Professional Service
    • Hackensack Meridian School of Medicine, Adjunct Associate Professor, 2018-present 
    • Seton Hall-Hackensack Meridian School of Medicine Curriculum Design Committee, 2016-2018
    • Editorial Board, Journal of Human on Chip Research Studies, 2016-present
    • APS-American Physiological Society, Editorial Review Board, Life Science Teaching Resources, 2014-present
    • AED-Alpha Epsilon Delta, National Health Preprofessional Honor Society, Northeast Region-I Director
    • ETS-Educational Testing Service, AP Biology Exam review and evaluation
    • External Review Committee Member, UMDNJ-Foundation Research Grants, 1979-1992
    Innovation and Entrepreneurship

    Supervised the research of a CHI Scholar on cataract induced blindness and cytokine profiling, 2014-2015

    Supervised undergraduate research projects on detection of salimetric biomarkers for neurodegenerative diseases, 2016-2018 

    Honors & Awards
    • Stevens 40-year Service Recognition
    • 2014 STEVENS Student Government Association Award- Distinguished Advisor of a Student Organization
    • 2014 Life Science Teaching Resources Fellow (APS-American Physiological Society)
    • 2013 Vision and Change Scholar Award (APS-American Physiological Society)
    • STEVENS Alumni Association, 25-year Service Award
    • NIH-Postdoctoral Fellowship
    • NIH-Predoctoral Fellowship
    • ESSO (Exon) Academic Scholarship
    Appointments

    Assistant Professor, Department of Chemistry and Chemical Engineering, Stevens Institute of Technology

    Associate Professor, Department of Chemistry and Chemical Biology, Stevens Institute of Technology

    Professional Societies

    American Physiological Society

    Society for Neuroscience

    AED-National Health Preprofessional Honor Society

    National Association of Advisors for the Health Professions

    Grants, Contracts & Funds
    • NSF Funded Educational Grants, Co-PI:  Pre-College Teacher Development in Science Project for Modern Biology and Honors Workshops:  Biochemistry Lecturer and Laboratory Director; 1979-1985
    • Howard Hughes Medical Institute (HHMI) Grant, Co-PI:  Chemical Biology Education Enhancement; 1989-1994
    • UPTAM, URP, Technogenesis:  Undergraduate Student Summer Research grants and projects
    • Women in Engineering Summer Courses for high school students; 1980-1990
    • ECOES-Exploring Career Options in Engineering and Science summer programs; 1986-1996
    Patents & Inventions

    "PEGylated Alginate-Hemoglobin-Based Nanoparticles for Oxygen Delivery," X. Yu, N. Kumbaraci, E. Lee filed 11/26, 2008 as U. S. Provisional Patent Application Serial No. 61/200,274

    Selected Publications
    Journals
    1. Nuran M. Kumbaraci. (Nov 14, 2019). "A Gargantuan Effort", Archives in Biomedical Engineering & Biotechnology, Iris Publishers. 3 (2), 1.  DOI: 10.33552/ABEB.2019.03.000560  .
    2. Kumbaraci, N. M.,. (1989). "Book Review, Molecular Neurobiology,", J. Am. Chem. Soc.,, (111(23)), 8767.
    3. Kumbaraci, N. M., Kiel, S. Y., Kovaleski, C. J.,. (1983). "Effects of Kepone on Acetylcholinesterase Activity in Goldfish Brain", The Bulletin of the NJ Acad. Sci., (28), 1.
    4. Kumbaraci, N. M., Kovaleski, C. J.,. (1983). "Effects of Kepone on Acetylcholinesterase Activity In Vitro", The Bulletin of the NJ Acad. Sci., (28), 2.
    5. Spathopoulos, S., Kumbaraci, N. M.,. (1982). "Effects of Kepone on Acetylcholinesterase Activity in Goldfish Tissues", The Bulletin of the NJ Acad. Sci., (27(1)), 30.
    6. Cappiello, L. L., Kumbaraci, N. M.,. (1982). "Beta-lactamase Inhibition and Antibiotic Activity of Newly Synthesized Compounds", The Bulletin of the NJ Acad. Sci., , (27(1)), 29.
    7. Kumbaraci, N. M., Kiel, S. Y., Kovaleski, C. J.,. (1982). "Effects of Chlordecone on Acetylcholinesterase Activity", The Physiologist, 4 (25), 314.
    8. Kumbaraci, N. M., Nastuk, W. L.,. (1980). "Caffeine-induced Sarcomeric Oscillations and Propagated Waves in Skeletal Muscle", Fed. Proc., (39), 529.
    9. Kumbaraci, N. M., Nastuk, W. L.,. (1978). "Effects of delta-9-tetrahydrocannabinol on Excitable Membranes and Neuromuscular Transmission", Soc. Neurosci. Abs., (4), 370.
    10. Kumbaraci, N. M.,. (1991). "Characterization of a Frog Skeletal Muscle Contraction Modulator", The Physiologist, (34(3)), 111.
    11. Kumbaraci, N. M., Passi, V., Xu, B.,. (1990). "Increased Complement Activity in Rat Serum After Tissue Injury", The FASEB Journal, (4(3)), 530.
    12. N. M. Kumbaraci, W. L. Nastuk. (1982). "Action of Caffeine in Excitation-Contraction Coupling of Frog Skeletal Muscle Fibres", The Journal of Physiology (London), 325 (1), 195-211.
    13. N. M. Kumbaraci, W.L. Nastuk. (1980). "Effects of Δ9-Tetrahydrocannabinol on Excitable Membranes and Neuromuscular Transmission", Molecular Pharmacology, 17, 344-349.
    Reports
    1. Kumbaraci, N. M.,. (2015). "Nerve Injury", Vision and Change TRC #3437, American Physiological Society.
    2. Kumbaraci, N. M.,. (2014). "Obesity and Metabolism", Archive Collection #2876, American Physiological Society.
    3. Kumbaraci, N. M.,. (2013). "Cardiovascular Changes with Exercise", Archive Resource # 7749, American Physiological Society.
    4. Kumbaraci, N. M.,. (2013). "Immunity", APS Archive Collection # C2570, American Physiological Society.
    Magazines
    1. Kumbaraci, N. M.,. (2007). "Roots of Chemical Biology", C&EN, (85(49)), 4.
    Books
    1. Nuran M. Kumbaraci. (2008). Chemical Biology Laboratory Manuals: Introductory Biology Laboratory (2013) and Cell Biology Laboratory (2014) , J. Wiley&Sons, 1-5 ed.
    Courses
    • BIO 281 Biology and Biotechnology
    • BIO 282 Introductory Biology Laboratory
    • BIO 381 Cell Biology
    • BIO 382 Biological Systems
    • BIO 484 Introduction to Molecular Genetics
    • CH 583 Physiology
    • CH 684 Molecular Biology Laboratory Techniques
    • CH 686 Immunology
    • CH 782 Selected Topics in Bioorganic Chemistry
    • CH 900 Masters Thesis in Chemistry/Chemical Biology
    • CH 496 Chemistry Project I
    • CH 781 Selected Topics in Biochemistry II