Dr. Woo Lee

GEORGE MEADE BOND PROFESSOR, CHEMICAL ENGINEERING & MATERIAL SCIENCE, DIRECTOR OF THE CENTER FOR MICROCHEMICAL SYSTEMS
School: Schaefer School of Engineering & Science
Department: Chemistry and Chemical Biology
Building: McLean
Room: McLean 510B
Phone: 201.216.8307
Email: wlee@stevens.edu
Website
Education
  • Ph.D. (Chemical Engineering) - 1990, Georgia Institute of Technology
  • M.S. (Chemical Engineering) - 1987, Auburn University
  • B.S. (Chemical Engineering) - 1985, University of Maryland
Research

My research interest resides with creating new devices using nanotechnology and microfluidics for transformative use. My lab is currently exploring two major frontiers of research: (1) microfluidic-based 3D human tissue and tumor models that can be used for preclinical drug evaluation and personalized medicine and (2) wearable graphene oxide (GO)-based biosensors for mobile health. These are student-centric efforts that are aimed at envisioning the transformative use of our ideas. My laboratory has produced 7 winners of the New Jersey Inventors Hall of Fame Graduate Student Award over the past decade. One of the students co-founded Bonbouton to commercialize our sensor technology. Also, several undergraduate and high school students perform research every year in my laboratory with notably one of them, David Monteiro, receiving the prestigious Barry Goldwater Scholarship in 2013.

Experience
  • Professor and Chair, Deparment of Chemistry and Chemical Biology,  Stevens Institute of Technology, 2020 - present
  • Professor, Department of Chemical Engineering and Materials Science, Stevens Institute of Technology, 1997-2020
  • George Meade Bond Chair of Chemical Engineering and Materials Science,Stevens Institute of Technology, 2009-2019
  • Chair, Department of Chemical Engineering and Materials Science, Stevens Institute of Technology, 2001-2005
  • Associate Professor, Department of Chemical Engineering and Materials Science, Stevens Institute of Technology, 1997-2001
  • Research Staff Member, Oak Ridge National Laboratory, July 1992 to July 1997
  • Research Scientist, United Technologies Research Center, February 1990 to July 1992
Honors & Awards
  • Master of Engineering (Honoris Causa): Stevens Institute of Technology, 2008
  • Academic Research Award: Printed Electronics USA Conference, 2011.
Professional Societies
  • Fellow: The American Ceramic Society since 2004.
  • Government Panels:  NSF-DMR, NIH-ISD, NIH-NIAID, ESF-Graphene, ESF-Bio
  • Member: AAAS and ACS
Grants, Contracts & Funds

41 grants and contracts received primarily from ARDEC, DOE, NIH, NSF, and ONR. 

Patents & Inventions

22 U.S Patents awarded

Selected Publications
Journals
  1. Z. Chen, J. Zilberberg, and W. Lee. (2020). "Pumpless Microfluidic Device with Open Top Cell Culture under Oscillatory Shear Stress", Biomedical Microdevices, doi.org/10.1007/s10544-020-00515-2.
  2. Y. Jin, Y. Zheng, S. Podkolzin, and W. Lee. (2020). "Band Gap of Reduced Graphene Oxide Tuned by Controlling Functional Groups", J. Mater. Chem. C, 8 4885-4894 .
  3. Y. Jin and W. Lee. (2019). "Crosslinking Stabilizes Electrical Resistance of Reduced Graphene Oxide in Humid Environment", Langmuir, 35 5427-5434 .
  4. Z. Chen, S. He, J. Zilberberg, and W. Lee. (2019). "Pumpless Platform for High-throughput Dynamic Multicellular Culture and Chemosensitivity Evaluation", Lab on a Chip, 19 254-261 .
  5. S. Choudhary, Q. Sun, C. Mannion, Y. Kissin, J. Zilberberg, and W.Y. Lee. (2018). "Hypoxic 3D Cellular Network Construction Preserves Ex vivo the phenotype of Primary Human Osteocytes", Tissue Engineering A, 24 458-468.
  6. S. Choudhary, C. Mannion, Y. Kissin, E. Dziopa, L. Tricoli, C. Albanese, W. Y. Lee, and J. Zilberberg. (2018). "Human Ex Vivo 3D Bone Model Recapitulates Osteocyte Response to Metastatic Prostate Cancer", Scientific Reports, 8 17975.
  7. Y. Jin. E Boon, E. Linh, and W. Lee. (2018). "Fabric-Infused Array of Reduced Graphene Oxide Sensors for Mapping of Skin Temperatures", Sensors and Actuators A, 280 92-98.
  8. Q. Sun, S. Choudhary, C. Mannion, Y. Kissin, J. Zilberberg, and W.Y. Lee. (2018). "Ex Vivo Replication of Phenotypic Functions of Human Primary Osteocytes through 3D Bone Tissue Construction", Bone, 106 148-155.
  9. J. Ding, S. Fu, E. Boon, R. Zhang, W.Y. Lee, F. Fisher, and E. H. Yang. (2017). "Graphene - Vertically Aligned Carbon Nanotube Hybrid on PDMS as Stretchable Electrodes", Nanotechnology, 28 465302.
  10. Q. Sun, S. Choudhary, C. Mannion, Y. Kissin, J. Zilberberg, and W.Y. Lee. (2017). "Ex Vivo Construction of Human Primary 3D-Networked Osteocytes", Bone, 105 245-252.
  11. W. Zhang, W.Y. Lee, and J. Zilberberg. (2016). "Tissue Engineering Platforms to Replicate the Tumor Microenvironment of Multiple Myeloma", Methods in Molecular Biology, 1513 171-191.
  12. E. P. Boon, L. T. Le, W. Y. Lee. (2016). "Inversion of temperature-resistance relationship by enlarged structural defects in graphene oxide", Carbon. 102 81-85.
  13. Q. Sun, Y. Gu, W. Zhang, L. Dziopa, J. Zilberberg, and W.Y. Lee. (2015). "Ex Vivo 3D Osteocyte Network Construction with Primary Murine Bone Cells", Bone Research. 3 152-163.3.
  14. W. Zhang, Y. Gu, Q. Sun, D.S. Siegel, P. Tolias, Z. Yang, W.Y. Lee, and J. Zilberberg. (2015). "Ex Vivo Maintenance of Primary Human Multiple Myeloma Cells through the Optimization of the Osteoblastic Niche", PLoS ONE. 10 (5), : e0125995.  doi:10.1371/journal.pone.0125995  .
  15. H. Qiu, V. Stepanov, A. DiStasio, A. Surapaneni, and W.Y. Lee. (2015). "Investigation of the Crystallization of RDX during Spray Drying", Powder Technology, 274 333-337.
  16. H. Qiu, T. Bechtold, L. Le, and W.Y. Lee. (2015). "Evaporative Assembly of Graphene Oxide for Electric Double-Layer Capacitor Electrode Application", Powder Technology, 270 192-196.
  17. M. Ervin, L. Le, and W.Y. Lee. (2014). "Inkjet-Printed Flexible Graphene-Based Supercapacitors", Electrochimica Acta, 147 610-616.
  18. Y. Gu, W. Zhang, H. Wang, and W.Y. Lee. (2014). "Chitosan Surface Enhances the Mobility, Cytoplasm Spreading, and Phagocytosis of Macrophages", Colloids and Surfaces B: Biointerfaces, 117 42-50.
  19. W. Zhang, W.Y. Lee, D. Siegel, P. Tolias and J. Zilberberg. (2014). "Patient-Specific 3D Microfluidic Tissue Model for Multiple Myeloma", Tissue Engineering C: Methods, 20 663-670.
  20. D. Kong, L.T. Le, Y. Li, J.L. Zunino, and W.Y. Lee. (2012). "Temperature-Dependent Electrical Properties of Graphene Inkjet-Printed on Flexible Materials", Langmuir, 28 13467−13472.
  21. A. C. Ihnen, A.M. Petrock, T. Chou, B.E. Fuchs, and W.Y. Lee. (2012). "Organic Nanocomposite Structure Tailored by Controlling Droplet Coalescence during Inkjet Printing", ACS Applied Materials & Interfaces, 4 4691−4699.
  22. H. Qiu, V. Stepanov, T. Chou, A. Surapaneni, A. R. Di Stasio, and W.Y. Lee. (2012). "Single-Step Preparation and Formulation of HMX Nanocrystals", Powder Technology, 226 235-238.
  23. X. Chen, Y. Gu, J.-H., Lee, W.Y. Lee, and H. Wang. (2012). "Multifunctional Surfaces with Biomimetic Nanofibres and Drug-Eluting Micro-Patterns for Infection Control and Bone Tissue Formation", European Cells and Materials, 24 237-248.
  24. J.-H. Lee, Y. Gu, H. Wang, and W. Y. Lee. (2012). "Microfluidic 3D Bone Tissue Model for High-Throughput Evaluation of Wound-Healing and Infection-Preventing Biomaterials", Biomaterials, 33 999-1006.
  25. Y. Gu, X. Chen, J.-H. Lee, D. Monteiro, H. Wang, and W.Y. Lee. (2012). "Inkjet Printed Antibiotic- and Calcium-Eluting Bioresorbable Nanocomposite Micropatterns for Orthopedic Implants", Acta Biomaterialia, 8 424-431.
  26. A.C. Ihnen, A.M. Petrock, T. Chou, P.J. Samuels, B.E. Fuchs, and W.Y. Lee. (2011). "Crystal Morphology Variation in Inkjet-Printed Organic Materials", Applied Surface Science, 258 827-833.
  27. L.T. Le, M.H. Ervin, H. Qiu, B.E. Fuchs, and W.Y. Lee. (2011). "Graphene Supercapacitor Electrodes Fabricated by Inkjet Printing and Thermal Reduction of Graphene Oxide", Electrochemistry Communications, 13 355-358.
  28. J.-H. Lee, H. Wang, J.B. Kaplan, and W.Y. Lee. (2011). "Microfluidic Approach to Create 3D Tissue Models for Biofilm Related Infection of Orthopaedic Implants", Tissue Engineering C: Methods, 17 39-48.
  29. H. Qiu, T. Chou, V. Stepanov, and A. Di Stasio, and W.Y. Lee. (2011). "RDX-based Nanocomposite Microparticles for Significantly Reduced Shock Sensitivity", J. of Hazardous Materials, 185 489-493.
  30. J.-H. Lee, H. Wang, J.B. Kaplan, W.Y. Lee. (2010). "Effects of S. epidermidis on Osteoblast Adhesion and Viability on Ti Alloy Surface in Microfluidic Co-Culture Environment", Acta Biomaterialia, 6 4422-4429.
  31. A.C. Ihnen, J.-H. Lee, and W.Y. Lee. (2010). "Effects of Disordered Hemispherical Micropatterns on Staphylococcus epidermidis Biofilm Formation", Colloids and Surfaces B: Biointerfaces, 75 601-607.
Courses
  • CHE 342 Heat and Mass Transfer
  • BME 342 Transport in Biological Systems
  • MT 602 Principles of Inorganic Materials Synthesis
  • E 344 Materials Processing