Carrie E. Perlman

School: Schaefer School of Engineering & Science
Department: Biomedical Engineering
Phone: 201.216.8779
Fax: 201.216.8196
  • B.S.M.E., Mechanical Engineering, MIT
  • M.S., Ph.D., Biomedical Engineering, Northwestern University
  • Postdoctoral training, Physiology & Cellular Biophysics and Pulmonary Division, Dept of Medicine, Columbia University

Lab Website

In the Lung Mechanics Lab, Dr. Perlman and her group combine mechanics, physiology and biophysics to understand and develop new treatments for pulmonary edema.

Openings are available for talented and enthusiastic Ph.D. students or postdoctoral fellows.  Please email Dr. Perlman, including a copy of your CV, to inquire.

Selected Publications
  1. Albert RK, Smith B, Perlman CE, Schwartz DA. "Is progression of pulmonary fibrosis due to ventilation-induced lung injury?", American Journal of Respiratory and Critical Care Medicine, in press.
  2. Nguyen TL, Perlman CE. "Tracheal acid or surfactant instillation raises alveolar surface tension", Journal of Applied Physiology 125: 1357-1367, 2018.
  3. Wu Y, Nguyen TL, Perlman CE. "Accelerated deflation promotes homogeneous airspace liquid distribution in the edematous lung", Journal of Applied Physiology 122: 739-751, 2017.
  4. Kharge AB, Wu Y, Perlman CE. "Sulforhodamine B interacts with albumin to lower surface tension and protect against ventilation injury of flooded alveoli", Journal of Applied Physiology 118: 355-364, 2015.
  5. Perlman CE. "Letter to the Editor: On modeling edematous alveolar mechanics", Journal of Applied Physiology 117: 937, 2014.
  6. Wu Y, Kharge AB, Perlman CE. "Lung ventilation injures areas with discrete alveolar flooding, in a surface-tension dependent fashion", Journal of Applied Physiology 117: 788-796, 2014.
  7. Kharge AB, Wu Y, Perlman CE. "Surface tension in situ in flooded alveolus unaltered by albumin", Journal of Applied Physiology 117: 440-451, 2014.
  8. Perlman CE, Wu Y. "In situ determination of alveolar septal strain, stress and effective Young's modulus: an experimental/computational approach", American Journal of Physiology - Lung Cellular & Molecular Physiology 307: L302-L310, 2014.
  9. Perlman CE, Mockros LF. "Predicted oxygenation efficacy of a thoracic artificial lung", ASAIO Jounral 58: 247-254, 2012.
  10. Wu Y, Perlman CE. "In situ methods for assessing alveolar mechanics", Journal of Applied Physiology 112: 519-526, 2012.
  11. Perlman CE, Lederer DJ, Bhattacharya J. "The micromechanics of alveolar edema", American Journal of Respiratory Cell and Molecular Biology 44: 34-39, 2011.
  12. Bhattacharya J, Perlman CE. "Letter to the Editor: Commentaries on Viewpoint--Standards for quantitative assessment of lung structure. Air space connectivity", Journal of Applied Physiology 109: 935-936, 2010.
  13. Kuo AS, Perlman CE, Mockros LF, Cook KE. "Pulmonic valve function during thoracic artificial lung attachment", ASAIO Journal 54: 197-202, 2008.
  14. Perlman CE and Bhattacharya J. "Alveolar expansion imaged by optical sectioning microscopy", Journal of Applied Physiology 103: 1037-1044, 2007.
  15. Lindert J, Perlman CE, Parthasarathi K, Bhattacharya J. "Chloride-dependent secretion of alveolar wall liquid determined by optical sectioning microscopy", American Journal of Respiratory Cell and Molecular Biology 36: 688-696, 2007.
  16. Perlman CE, Mockros LF. "Hemodynamic consequences of thoracic artificial lung attachment configuration: a computational model", ASAIO Journal 53: 50-64, 2007.
  17. Perlman CE, Cook KE, Seipelt R, Mavroudis C, Backer CL, Mockros LF. "In vivo hemodynamic responses to thoracic artificial lung attachment", ASAIO Journal 51: 412-25, 2005.
  18. Cook KE, Perlman CE, Seipelt R, Backer CL, Mavroudis C, Mockros LF. "Hemodynamic and gas transfer properties of a compliant thoracic artificial lung", ASAIO Journal 51: 404-11, 2005.
  19. Boschetti F, Cook KE, Perlman CE, Mavroudis LF, Backer CL, Mockros LF. "Blood flow pulsatility effects upon oxygen transfer in artificial lungs", ASAIO Journal 49: 678-686, 2003.
  20. Boschetti F, Perlman CE, Cook KE, Mockros LF. "Hemodynamic effects of attachment modes and device design of a thoracic artificial lung", American Society for Artificial Internal Organs (ASAIO) Journal 46: 42-48, 2000.