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This course serves as an introduction to chemical engineering for those with no previous training in the field. Among the topics covered are mass and energy balances, and equilibrium stagewise operations.
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This introductory course in chemical engineering covers mass, heat and momentum transfer.
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This introductory course in chemical engineering covers reaction kinetics and chemical reactor design.
Prerequisites:
CHE 501 Mass and Energy Balances, Stagewise Operations
(0-0-3)(Lec-Lab-Credit Hours)
This course serves as an introduction to chemical engineering for those with no previous training in the field. Among the topics covered are mass and energy balances, and equilibrium stagewise operations.
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Transport Phenomena
(0-0-3)(Lec-Lab-Credit Hours)
This introductory course in chemical engineering covers mass, heat and momentum transfer.
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This course is intended to teach the basis of safety in pilot plants, laboratory and similar research operations. It will focus on the practical concerns faced in industry and highlight those areas not readily available elsewhere.
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Pharmaceutical manufacturing is vital to the success of the technical operations of a pharmaceutical company. This course is approached from the need to balance company economic considerations with the regulatory compliance requirements of safety, effectiveness, identity, strength, quality, and purity of the products manufactured for distribution and sale by the company. Overview of chemical and biotech process technology and equipment, dosage forms and finishing systems, facility engineering, health, safety, & environment concepts, and regulatory issues.
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This course reviews the 12 elements of the Process Safety Management (PSM) model created by the Center for Chemical Process Safety of the American Institute of Chemical Engineers. PSM systems were developed as an expectation/demand of the public, customers, in-plant personnel, stockholders and regulatory agencies because reliance on chemical process technologies were not enough to control, reduce and prevent hazardous materials incidents. PSM systems are comprehensive sets of policies, procedures and practices designed to ensure that barriers to major incidents are in place, in use and effective. The objectives of this course are to: define PSM and why it is important, describe each of the 12 elements and their applicability, identify process safety responsibilities, give real examples and practical applications to help better understand each element, share experiences and lessons learned of all participants, and assess the quality and identify enhancements to student's site PSM program.
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Current Good Manufacturing Practice compliance issues in design of pharmaceutical and biopharmaceutical facilities. Issues related to process flow, material flow, and people flow, and A&E mechanical, industrial, HVAC, automation, electrical, and computer. Bio-safety levels. Developing effective written procedures, so that proper documentation can be provided, and then documenting through validation that processes with a high degree of assurance do what they are intended to do. Levels I, II, and III policies. Clinical phases I, II, III and their effect on plant design. Defending products against contamination. Building quality into products.
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This course provides a broad overview of topics related to the design and operations of modern biopharmaceutical facilities. It covers process, utilities and facility design issues, and encompasses all major manufacturing areas, such as fermentation, harvest, primary and final purification, media and buffer preparation, equipment cleaning and sterilization, and critical process utilities. Unit operations include cell culture, centrifugation, conventional and tangential flow filtration, chromatography, solution preparation, and bulk filling. Application of current Good Manufacturing Practices and Bioprocessing Equipment Standards (BPE-2002) will be discussed.
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Validation of a pharmaceutical manufacturing process is an essential requirement with respect to compliance with Good manufacturing Practices (GMP) contained within the Code of Federal Regulations (21 CFR). Course covers validation concepts for plant, process, cleaning, sterilization, filtration, analytical methods, and computer systems; GAMP (Good Automated Manufacturing Practice), IEEE SQAP, and new electronic requirements – 21 CFR Part 11. Master validation plan, IQ, OQ, and PQ protocols, and relationships to GMP. National (FDA) and international (EU) regulatory affairs for cGMP (current Good Manufacturing Practice) and cGLP (current Good Laboratory Practice) requirements in development, manufacturing, and marketing. Handling the FDA inspection.
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Computers and computerized systems are ubiquitous in pharmaceutical manufacturing. Validation of these systems is essential to assure public safety and compliance with appropriate regulatory issues regarding validation: GMP, GCP, 21CFR Part 11, etc. This course covers validation concepts for various classes of computerized systems and applications used in the pharmaceutical industry; importance of requirements engineering in validation; test protocols and design; organizational maturity considerations.
Prerequisites:
CHE 540 Validation and Regulatory Affairs in Pharmaceutical Manufacturing
(0-0-3)(Lec-Lab-Credit Hours)
Validation of a pharmaceutical manufacturing process is an essential requirement with respect to compliance with Good manufacturing Practices (GMP) contained within the Code of Federal Regulations (21 CFR). Course covers validation concepts for plant, process, cleaning, sterilization, filtration, analytical methods, and computer systems; GAMP (Good Automated Manufacturing Practice), IEEE SQAP, and new electronic requirements – 21 CFR Part 11. Master validation plan, IQ, OQ, and PQ protocols, and relationships to GMP. National (FDA) and international (EU) regulatory affairs for cGMP (current Good Manufacturing Practice) and cGLP (current Good Laboratory Practice) requirements in development, manufacturing, and marketing. Handling the FDA inspection.
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Designed to provide the process engineers with the background necessary to understand and work with microprocessor -based systems. Topics include: introduction and overview of microprocessor-based technology in chemical engineering; analog and digital signal conditioning, data transmission and serial interfacing using RS-232C and GPIB IEEE-488standards; analog-to-digital conversion and sampling; digital-to-analog conversion; digital I/O, switches/relays, and power supplies; microprocessor-based sensors, transducers and actuators; programmable logic controllers and batch process control; software packages for data-acquisition and control.
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Development and evaluation of processing schemes; analysis of process circuits; establishing design criteria; process design; evaluation and selection of process equipment: economic analysis and evaluation; applications to chemical, biochemical, waste treatment, energy and other processes of current interest.
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Selection, design, and scaling of separation processes using principles of momentum, energy, and mass transfer; applications to novel as well as to conventional separation techniques.
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The ultimate goal of this course is to prepare students to undertake the analysis of the most difficult problems in equilibrium stage operations. The problems typically, involve one or more columns with components exhibiting highly non-ideal behavior. This class of problems includes azeotropic distillation, extractive distillation, columns with more than one liquid phase, and a variety of other anomalies. Lack of complete equilibrium dat is not uncommon. Extensive use is made of commercialsoftware in the solution of problems. The course concludes with the assignment of an industrial problem, a substantial project, which requires that the students exercise virtually all techniques studied.
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Concepts of similarity and dimensional analysis; models, scaling, correlation of physical and engineering properties, applications in chemical engineering design.
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This course supplements the clasical undergraduate thermodynamics course by focusing on physical and thermodynamic properties, and phase equilibria. A variety of equations of state, and their applicability, are introduced as are all of the important liquid activity coefficient equations. Customization of both vapor and liquid equations is introduced by appropriate methods of applied mathematics. Vapot-liquid, liquid-liquid, vapor-liquid-liquid and solid-liquid equilibria are considered with rigor. Industrial applications are employed. A variety of methods for estimating physical and thermodynamic properties are introduced. Students are encouraged to use commercial software in applications. The course concludes with an introduction to statistical thermodynamics.
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The course covers finished product manufacturing and packaging systems in the pharmaceutical industry, concentrating on the oral solid dosage forms. Process unit operations include blending, granulating, size reduction, drying, compressing, and coating for tablets, as well as blending and filling for capsules. Design and operation of packaging equipment for tablet and capsule counting, capping, security sealing, labeling, cartoning, and case packing will be considered. Approach for development of project documentation, such as equipment specifications, purchase orders, test plans, and validation documents will be presented. Use of computer simulation tools for system development and improvement will be discussed. Term paper project will require students to collectively design a solid dosage manufacturing and packaging facility, considering selection of processing and packaging equipment, material flow, development of commissioning and qualification plan and protocols.
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Generalized approach to differential and macroscopic balances: constitutive material equations; momentum and energy transport in laminar and turbulent flow; interphase and intraphase transport; dimensionless correlations
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Bulk active pharmaceutical ingredient manufacturing and unit operations.
Process scale-up. Transport processes, including mass, heat, and momentum transfer. Process synthesis, analysis, and design. Traditional separation processes, including distillation, evaporation, extraction, crystallization, and absorption. New separation processes, including pressure swing adsorption, molecular sieves, ion exchange, reverse osmosis, microfiltration, nanofiltration, ultrafiltration, diafiltration, gas permeation, pervaporation, supercritical fluid extraction, and high performance liquid chromatography (HPLC). Batch and continuous reactors for homogeneous, heterogeneous, catalytic, and non-catalytic reactions.
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This course will introduce students to the modeling and simulation applications in the pharmaceutical manufacturing. Learn the basics of discreet event simulation and use commercially available software to develop models of various manufacturing and service systems. Approaches to the development of conceptual and computer models, data collection and analysis, model verification and validation, simulation output analysis are discussed. Learn how to model chemical, biochemical and separation processes in pharmaceutical manufacturing using process simulation software. Develop material balances, stream reports, operations and equipment Gantt charts, conduct process debottlenecking and cost analysis.
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The course begins with a review of traditional separation processes such as distillation, evaporation, extraction, crystallization and absorption. New topics in separation which are covered include pressure swing adsorption, molecular sieves, ion exchange, reverse osmosis, microfiltration, nano-filtration, ultrafiltration, diafiltration, gas permeation, pervaporation, supercritical fluid extraction, and liquid chromatography. Industrial applications, design considerations, and engineering analysis of these separation topics are covered.
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Proven techniques and creative tools presented for design, development, and delivery of biopharmaceutical manufacturing facilities. Includes skills and knowledge in bioprocessing requirements, equipment and facility requirements, project management as well as regulatory guidelines and big-picture drug development. Also corporate capital management processes to functionally meet corporate requirements from pre-clinical to commercial scale of operations, qualifications to pass regulatory inspections, achieving faster time-to-market, but not breaking the corporate treasury bank. Course also explores trends in new equipment technology such as disposables or single-use product, new design concepts in aseptic manufacturing, barrier and isolation technologies, new FDA thinking in risk-based compliance approach, process analytical technology, capital project planning and management.
Prerequisites:
CHE 530 Introduction to Pharmaceutical Manufacturing
(0-0-3)(Lec-Lab-Credit Hours)
Pharmaceutical manufacturing is vital to the success of the technical operations of a pharmaceutical company. This course is approached from the need to balance company economic considerations with the regulatory compliance requirements of safety, effectiveness, identity, strength, quality, and purity of the products manufactured for distribution and sale by the company. Overview of chemical and biotech process technology and equipment, dosage forms and finishing systems, facility engineering, health, safety, & environment concepts, and regulatory issues.
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Good Manufacturing Practice in Pharmaceutical Facilities Design
(0-0-3)(Lec-Lab-Credit Hours)
Current Good Manufacturing Practice compliance issues in design of pharmaceutical and biopharmaceutical facilities. Issues related to process flow, material flow, and people flow, and A&E mechanical, industrial, HVAC, automation, electrical, and computer. Bio-safety levels. Developing effective written procedures, so that proper documentation can be provided, and then documenting through validation that processes with a high degree of assurance do what they are intended to do. Levels I, II, and III policies. Clinical phases I, II, III and their effect on plant design. Defending products against contamination. Building quality into products.
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Bioprocess Technology in API Manufacturing
(0-0-3)(Lec-Lab-Credit Hours)
This course provides a broad overview of topics related to the design and operations of modern biopharmaceutical facilities. It covers process, utilities and facility design issues, and encompasses all major manufacturing areas, such as fermentation, harvest, primary and final purification, media and buffer preparation, equipment cleaning and sterilization, and critical process utilities. Unit operations include cell culture, centrifugation, conventional and tangential flow filtration, chromatography, solution preparation, and bulk filling. Application of current Good Manufacturing Practices and Bioprocessing Equipment Standards (BPE-2002) will be discussed.
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Introduction to Project Management
(0-0-3)(Lec-Lab-Credit Hours)
This course deals with the problems of managing a project, which is defined as a temporary organization of human and non-human resources, within a permanent organization, for the purpose of achieving a specific objective; both operational and conceptual issues will be considered. Operational issues include definition, planning, implementation, control and evaluation of the project. Conceptual issues include project management vs. hierarchical management, matrix organization, project authority, motivation and morale. Cases will be used to illustrate problems in project management and how to resolve them.
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Water & steam systems: (water used as excipient, cleaning agent, or product diluent) water quality selection criteria; generation, storage and
distribution systems; bio-burden control; USP PWS (purified water systems) and USP WFI (water for injection) systems; engineering considerations, including specification, design, installation, validation, operation, testing, and maintenance; common unit operations, including deionization, reverse osmosis, distillation, ultrafiltration, and ozonation systems; process considerations, including pretreatment, storage and distribution, materials of construction, microbial control, pyrogen control, and system maintenance; FDA requirements; clean-in-place systems; steam generation and distribution systems.
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Analysis of batch and continuous chemical reactions for homogeneous, heterogeneous, catalytic, and non-catalytic reactions; influence of temperature, pressure, reactor size and type, mass and heat transport on yield and product distribution; design criteria based on optimal operating conditions and reactor stability will be developed.
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This course describes the application of catalysis to modern air pollution
control. A practical description of catalysts and their fundamental
properties provides a foundation for understanding modern catalytic converters used for reducing hydrocarbon, carbon monoxide, and nitric oxide emissions from gasoline and diesel fueled vehicles, power plants, chemical facilities, etc. It is intended for graduate students in any engineering or science discipline interested in environmental control technology.
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| | | (0-0-3) (Lec-Lab-Credit Hours)
The objective of this course is to provide the student with the engineering tools and knowledge required to design and deploy Process Analytical Technology (PAT) solutions in pharmaceutical drug substance and drug product manufacturing. This course provides in-depth coverage of current PAT technologies. At the conclusion of this course, students will understand the engineering theory, principles, and mathematics required to design and deploy these technologies in a pharmaceutical manufacturing environment in compliance with FDA and international regulations. Topics covered include: analyzer types and principals of operation, chemometric techniques for multivariate analysis, multivariate process models, dynamic process control, and advanced pattern recognition techniques. In addition, the course will cover the technical aspects of real-time data management and 21 CFR Part 11 compliance.
Prerequisites:
CHE 530
(0-0-3)(Lec-Lab-Credit Hours)
Pharmaceutical manufacturing is vital to the success of the technical operations of a pharmaceutical company. This course is approached from the need to balance company economic considerations with the regulatory compliance requirements of safety, effectiveness, identity, strength, quality, and purity of the products manufactured for distribution and sale by the company. Overview of chemical and biotech process technology and equipment, dosage forms and finishing systems, facility engineering, health, safety, & environment concepts, and regulatory issues.
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Mathematical modeling and identification of chemical processes. State-space process representation and analysis: stability, observability, controllability and reach-ability. Analysis and design of advanced control systems: internal model control, dynamic matrix control and model predictive control. Synthesis of multivariable control systems: interaction analysis, singular value decomposition, decoupler design. Continuous and sampled-data systems, on-line process identification. State and parameter estimation techniques: Luenberger observer and Kalman filter. Knowledge of Laplace transforms, material and energy balances, computer programming and matrix algebra is required.
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The course comprises a series of workshops, employing an industrial process simulator, Aspen Plus, which explore the primary components required to simulate a chemical process. Most workshops have embedded irregularities designed to heighten the student awareness of the types of errors that could arise when using simulation software. The workshops include facilities to exercise and customize a wide variety of physical and thermodynamic properties as the students develop process models. Heavy concentration is on the equations describing the models used. As the experience level of the students rises, workshops designed to introduce complicated industrial flowsheets are employed.
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Stress-strain relationships, theory of linear viscoelasticity and relaxation spectra, temperature dependence of viscoelastic behavior, dielectric properties, dynamic mechanical and electrical testing, molecular theories of flexible chains, statistical mechanics and thermodynamics of rubber-like undiluted systems, morphology of high polymers.
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Molecular and continuum mechanical constitutive equations for viscoelastic fluids; analysis of viscometric experiments to evaluate the viscosity and normal stress functions: dependence of these functions on the macromolecular structure of polymer melts: solution of isothermal and nonisothermal flow problems with non-Newtonian fluids which are encountered in polymer processing; development of design equations for extruder dies and molds.
Prerequisites:
CHE 630
(0-0-3)(Lec-Lab-Credit Hours)
Generalized approach to differential and macroscopic balances: constitutive material equations; momentum and energy transport in laminar and turbulent flow; interphase and intraphase transport; dimensionless correlations
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Descriptions of various polymer processing operations and processing requirements of biomedical products, principles of processing of polymers covering melting, pressurization, mixing, devolatilization, shaping using extrusion, spinning, blowing, coating, calendering and molding technologies, surface treatment and sterilization, applications in the areas of prostheses and artificial organs and packaging of various biomedical devices.
Prerequisites:
CHE 630
(0-0-3)(Lec-Lab-Credit Hours)
Generalized approach to differential and macroscopic balances: constitutive material equations; momentum and energy transport in laminar and turbulent flow; interphase and intraphase transport; dimensionless correlations
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Analysis and design of experimental and industrial polymerization reactors for various polymerization mechanisms: relationship between design parameters and polymer structure, yield and average molecular weight: kinetic and statistical methods; batch and continuous, addition and condensation polymerization in bulk, solution, suspension and emulsion.
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A treatment of polymer processing machinery with emphasis on the design of components to implement the various elementary steps involved, and subsequent assembly of these components into processing machines. Use is made of computational models. Principles of control systems are applied to processing machinery. The primary objective is to stimulate creative approaches to the design of processing machinery rather than to familiarize the student with the details of existing machinery.
Prerequisites:
CHE 672
(0-0-3)(Lec-Lab-Credit Hours)
Descriptions of various polymer processing operations and processing requirements of biomedical products, principles of processing of polymers covering melting, pressurization, mixing, devolatilization, shaping using extrusion, spinning, blowing, coating, calendering and molding technologies, surface treatment and sterilization, applications in the areas of prostheses and artificial organs and packaging of various biomedical devices.
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Recent advances in polymer blend and composite formation; the role of melt rheology in component selection and the resulting morphology; melt mixing processes and equipment; models for predicting processing and performance characteristics; morphology generation and control in manufacturing processes; sample calculations and case histories for polyblends used in film blowing, blow molding and injection molding.
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Principal manufacturing methods utilizing molds and dies; mold and die design characteristics dictated by functional requirements; interaction between molds/dies and processing machinery; mathematical models of forming processes including: flow through dies and into molds, solidification, heat transfer and reaction (in reactive processing); end-product properties (morphology, bulk properties, tolerances, appearance) and operating conditions in alternative manufacturing methods; materials and manufacturing methods for molds and dies; case studies.
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Design of polymeric products; design criteria based upon product functions and geometry; material selection by property assessment; selection of molds, dies, and special manufacturing devices (e.g., mold inserts); selection of appropriate forming process (injection, rotational or blow-molding, extrusion, etc.), and determination of optimum operating conditions (such as temperature, pressure, cycle or residence time). Case histories of failure.
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Discussion of models for flow and deformation in polymers, and a treatment of measurable rheological properties. Analysis of thermoplastic and thermosetting resins for processability. Use of experimental data to determine parameters of the constitutive equations. Laboratory includes use of state-of-art equipment in elongational, rotational, and capillary viscometry.
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A survey course covering the chemical, biological and material science aspects of interfacial phenomena. Applications to adhesion, biomembranes, colloidal stability, detergency, lubrication, coating, fibers, and powders - were surface properties play an important role. Prerequisites: Physical Chemistry and Thermodynamics.
Prerequisites:
CH 321
(3-0-3)(Lec-Lab-Credit Hours)
Laws of thermodynamics, thermodynamic functions, and the foundations of statistical thermodynamics. The chemical potential is applied to phase equilibria, chemical reaction equilibria, and solution theory, for both ideal and real systems.
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(3-4-4)(Lec-Lab-Credit Hours)
Chemical kinetics, solution theories with applications to separation processes, electrolytes, polyelectrolytes, regular solutions and phase equilibria, and laboratory practice in the measurements of physical properties and rate processes.
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(0-3-2)(Lec-Lab-Credit Hours)
This course includes both experimentation and open-ended design problems that are integrated with the Materials Processing course taught concurrently. Core design themes are further developed.
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This course deals with the principles of light interactions with biological and biomedical-relevant systems. The enabling aspects of nanotechnology for advanced biosensing, medical diagnosis, and therapeutically treatment will be discussed.
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Lectures by department faculty, guest speakers, and doctoral students on recent research.
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Selected topics of current interest in the field of chemical engineering will be treated from an advanced point of view.
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The course is designed to enable students to attack a variety of chemical engineering problems which lend themselves to solution by numerical methods as opposed to classical mathematics. Problems that do not fir the mold "use existing software" are illustrated. The students are encouraged to create their own software to solveproblems. For this purpose students are given an introduction to the Visual Basic programming language. Students are also encouraged to use more advanced methods in Excel. Examples and homework assignments are drawn from industrial experience when possible.
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techniques in chemical engineering analysis; tensor analysis, numerical
methods, operational mathematics, probabilistic and statistical methods,
nonlinear equations and stability theories.
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A critical review of current theories and experimental aspects of polymer science and engineering.(Three to Six credits.)
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One to six credits. Limit of six credits for the degree of Master of Engineering (Chemical).
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One to six credits. Limit of six credits for the degree of Doctor of Philosophy.
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For the degree of Chemical Engineer. (One to six credits.)
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A participating seminar on topics of current interest and importance in
Chemical Engineering
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For the degree of Master of Engineering (Chemical). Five to ten credits with departmental approval.
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Design project for the degree of Chemical Engineer. Hours and credits to be arranged. Eight to fifteen credits.
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Original research leading to the doctoral dissertation. Hours and credits to be arranged.
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An introduction to the structures/properties relationships of materials principally intended for students with a limited background in the field of materials science. Topics include: structure and bonding, thermodynamics of solids, alloys and phase diagrams, mechanical behavior, electrical properties and the kinetics of solid state reactions. The emphasis of this subject is the relationship between structure and composition, processing (and synthesis), properties and performance of materials.
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| | (0-0-3) (Lec-Lab-Credit Hours)
This course deals with aspects of the technology of processing procedures
involved in the fabrication of semiconductor devices. Topics include crystal
growth, epitaxy, silicon oxide growth, impurity doping, ion implantation,
photo and electron beam lithography, etching, sputtering, thin film
metallization, passivation and packaging. A description of these fabrication techniques used for discrete devices (e.g., bi-polar transistor, field effect transistor, light-emitting diode and solar cell), as well
as large-scale integrated thin film circuits, will be presented.
Prerequisites:
MT 239 Materials
(0-0-3)(Lec-Lab-Credit Hours)
An introduction to the important engineering properties of materials, to the scientific understanding of those properties and to the methods for controlling them. The course will include metals, semiconductors, ceramics, polymers and their composites and their applications in structures, machine elements, electronic, optical and magnetic devices.
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Introduction to Materials Science and Engineering
(0-0-3)(Lec-Lab-Credit Hours)
An introduction to the structures/properties relationships of materials principally intended for students with a limited background in the field of materials science. Topics include: structure and bonding, thermodynamics of solids, alloys and phase diagrams, mechanical behavior, electrical properties and the kinetics of solid state reactions. The emphasis of this subject is the relationship between structure and composition, processing (and synthesis), properties and performance of materials.
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Description of simple physical models which account for electrical conductivity and thermal properties of solids. Basic crystal lattice structures, X-ray diffraction, and dispersion curves for phonons and electrons in reciprocal space. Energy bands, Fermi surfaces, metals, insulators, semiconductors, superconductivity, and ferromagnetism. Fall semester. Typical text: Kittel, Introduction to Solid State Physics
Prerequisites:
PEP 242 Modern Physics
(3-0-3)(Lec-Lab-Credit Hours)
Simple harmonic motion, oscillations and pendulums; Fourier analysis; wave properties; wave-particle dualism; the Schrödinger equation and its interpretation; wave functions; the Heisenberg uncertainty principle; quantum mechanical tunneling and application; quantum mechanics of a particle in a "box," the hydrogen atom; electronic spin; properties of many electron atoms; atomic spectra; principles of lasers and applications; electrons in solids; conductors and semiconductors; the n-p junction and the transistor; properties of atomic nuclei; radioactivity; fusion and fission. Spring Semester.
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Electromagnetism
(0-0-3)(Lec-Lab-Credit Hours)
Second semester, three credits. Electrostatics; Coulomb-Gauss Law; Poisson-Laplace equations; boundary value problems; image techniques, dielectric media; magnetostatics; multipole expansion, electromagnetic energy, electromagnetic induction, Maxwell's equations, electromagnetic waves, waves in bounded regions, wave equations and retarded solutions, simple dipole antenna radiation theory, transformation law of electromagnetic fields.
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| | (0-0-3) (Lec-Lab-Credit Hours)
Intended as an introduction for the student who is familiar with materials science, this course first reviews the properties of materials that are relevant to their application in the human body. It then introduces proteins, cells, tissues, and their reactions to foreign materials, and the degradation of these materials in the human body. The course then treats the various implants, burn dressings, drug delivery systems, biosensors, artificial organs, and elements of tissue engineering.
Prerequisites:
MT 501 Introduction to Materials Science and Engineering
(0-0-3)(Lec-Lab-Credit Hours)
An introduction to the structures/properties relationships of materials principally intended for students with a limited background in the field of materials science. Topics include: structure and bonding, thermodynamics of solids, alloys and phase diagrams, mechanical behavior, electrical properties and the kinetics of solid state reactions. The emphasis of this subject is the relationship between structure and composition, processing (and synthesis), properties and performance of materials.
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| | (0-0-3) (Lec-Lab-Credit Hours)
Theory and practical means for predicting the behavior of materials under stress. Elastic and plastic deformation, fracture and high-temperature deformation (creep).
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An overview of microelectronics and photonics science and technology. It provides the student who wishes to specialize in their application, physics or fabrication with the necessary knowledge of how the different aspects are interrelated. It is taught in three modules: design and applications, taught by EE faculty; operation of electronic and photonic devices, taught by physics faculty; fabrication and reliability, taught by the materials faculty.
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| | (3-0-3) (Lec-Lab-Credit Hours)
This course will cover topics encompassing the fundamental subject matter for the design of optical systems. Topics will include optical system analysis, optical instrument analysis, applications of thin film coatings and opto-mechanical system design in the first term. The second term will cover the subjects of photometry and radiometry, spectrographic and spectrophotometric systems infrared radiation measurement and instrumentation, lasers in optical systems, and photon-electron conversion.
Prerequisites:
EE 509 Intermediate Waves and Optics
(0-0-3)(Lec-Lab-Credit Hours)
The general study of field phenomena; scattering and vector fields and waves; dispersion, phase, and group velocity; interference, diffraction, and polarization; coherence and correlation; and geometric and physical optics.
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Modern Optics
(3-0-3)(Lec-Lab-Credit Hours)
Concepts of geometrical optics for reflecting and refracting surfaces, thin and thick lens formulations, optical instruments in modern practice, interference, polarization and diffraction effects, resolving power of lenses and instruments, X-ray diffraction, introduction to lasers and coherent optics, principles of holography, concepts of optical fibers, optical signal processing. Spring semester.
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Intermediate Waves and Optics
(3-0-3)(Lec-Lab-Credit Hours)
The general study of field phenomena; scalar and vector fields and waves; dispersion phase and group velocity; interference, diffraction and polarization; coherence and correlation; geometric and physical optics. Typical text: Hecht and Zajac, Optics. Spring semester.
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| | (3-0-3) (Lec-Lab-Credit Hours)
This course will cover topics encompassing the fundamental subject matter for the design of optical systems. Topics will include optical system analysis, optical instrument analysis, applications of thin film coatings and opto-mechanical system design in the first term. The second term will cover the subjects of photometry and radiometry, spectrographic and spectrophotometric systems infrared radiation measurement and instrumentation, lasers in optical systems, and photon-electron conversion.
Prerequisites:
EE 509 Intermediate Waves and Optics
(0-0-3)(Lec-Lab-Credit Hours)
The general study of field phenomena; scattering and vector fields and waves; dispersion, phase, and group velocity; interference, diffraction, and polarization; coherence and correlation; and geometric and physical optics.
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Modern Optics
(3-0-3)(Lec-Lab-Credit Hours)
Concepts of geometrical optics for reflecting and refracting surfaces, thin and thick lens formulations, optical instruments in modern practice, interference, polarization and diffraction effects, resolving power of lenses and instruments, X-ray diffraction, introduction to lasers and coherent optics, principles of holography, concepts of optical fibers, optical signal processing. Spring semester.
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Intermediate Waves and Optics
(3-0-3)(Lec-Lab-Credit Hours)
The general study of field phenomena; scalar and vector fields and waves; dispersion phase and group velocity; interference, diffraction and polarization; coherence and correlation; geometric and physical optics. Typical text: Hecht and Zajac, Optics. Spring semester.
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| | (3-0-3) (Lec-Lab-Credit Hours)
This course is an in depth treatment of the principles and practice associated with using solar radiation as an alternate energy source. It examines the science of solar radiation, technologies for its capture and the design principles that are used to apply solar energy in building design.
Prerequisites:
MT 518 Solar Energy: Theory & Application
(3-0-3)(Lec-Lab-Credit Hours)
This course is an in depth treatment of the principles and practice associated with using solar radiation as an alternate energy source. It examines the science of solar radiation, technologies for its capture and the design principles that are used to apply solar energy in building design.
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| | (0-0-3) (Lec-Lab-Credit Hours)
Composite material characterization; composite mechanics of plates, panels, beams, columns, and rods integrated with design procedures; analysis and design of composite structures; joining methods and procedures; introduction to manufacturing processes of filament winding, braiding, injection, compression and resin transfer molding, machining and drilling; and industrial applications.
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| | (0-0-3) (Lec-Lab-Credit Hours)
This course deals with the principles and practices of
thin-film deposition by physical and chemical methods, the processes and phenomenawhich influence the structural, chemical and physical attributes of films and how to characterize them, and assorted film properties. Special topicsinclude epitaxy in semiconductor films, interdiffusion and reactions, film stress, electrical and magnetic properties, optical properties, surface modification by laser and ion-beam methods, and protective and metallurgical coatings.
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| | (0-0-3) (Lec-Lab-Credit Hours)
A phenomenological and theoretical introduction to the
field of surface science including experimental techniques and engineering
applications. Topics will include: thermodynamics and structure of
surfaces, surface diffusion, electronic properties and space-charge effects,
physisorption and chemisorption.
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| | (0-0-3) (Lec-Lab-Credit Hours)
Lectures, demonstrations and laboratory experiments, selected from among the following topics, depending on student interest: vacuum technology; thin-film preparation; scanning electron microscopy; LEED; infrared spectroscopy, ellipsometry; electron spectroscopies (Auger, photoelectron, field emission); ion spectroscopies (SIMS, IBS; surface properties-area), roughness and surface tension.
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| | (3-0-3) (Lec-Lab-Credit Hours)
This course provides an in-depth treatment of how to transfer the latest solar thermal technology available to real world applications. It takes the student through the various phases of development of a solar space heating and photovoltaic integrated building; review occupant’s requirements, site analysis, design concept, solar system design, cost estimates, building design, performance predictions and construction. The emphasis of the class is on solar system design methods, economic optimization of solar systems and installation.
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| | (0-0-3) (Lec-Lab-Credit Hours)
The thermodynamics and kinetics of electrochemical cells, voltage-current relationships during corrosion and passivation. Stress corrosion, degradation of ceramics, polymers and composites, high-temperature corrosion and wear of materials.
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| | (0-0-3) (Lec-Lab-Credit Hours)
This course provides a rational approach to the selection
of engineering materials as part of the design process. The emphasis is
on the use of Materials Selection charts that embody the properties of
materials plotted against various quantitative design criteria. Such
criteria can be determined for a particular application in terms of mechanical indices or indices relating to shape and/or processing considerations. In this manner, materials are chosen with limited subjectivity and in a manner that lends itself to computer-based design. Case studies are extensively used to provide illustration.
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| | (0-0-3) (Lec-Lab-Credit Hours)
A lecture and laboratory course that introduces basic concepts in the design and operation of transmission electron microscopes and scanning electron microscopes as well as the fundamental aspects of image interpretation and diffraction analysis. Topics include: electron sources, electron optics, kinematic and dynamic theory of electron diffraction, and spectroscopic analysis. A typical textbook is Goodhew and Humphreys, Electron Microscopy and Analysis.
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| | (0-0-3) (Lec-Lab-Credit Hours)
Basic plasma physics; some atomic processes; and plasma diagnostics. Plasma production; DC glow discharges, and RF glow discharges; and magnetron discharges. Plasma-surface interaction; sputter deposition of thin films; reactive ion etching, ion milling and texturing, and electron-beam-assisted chemical vapor deposition; and ion implantation. Sputtering systems; ion sources; electron sources; and ion beam handling. Typical text: Chapman, Glow Discharge Processes; Brodie, Muray, The Physics of Microfabrication.
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| | (0-0-3) (Lec-Lab-Credit Hours)
This course introduces fundamentals of semiconductors and basic building blocks of semiconductor devices that are necessary for understanding semiconductor device operations. It is for first-year graduate students and upper-class undergraduate students in electrical engineering, applied physics, engineering physics, optical engineering and materials engineering who have no previous exposure to solid state physics and semiconductor devices. Topics covered will include description of crystal structures and bonding; introduction to statistical description of electron gas; free-electron theory of metals; motion of electrons in periodic lattices-energy bands; Fermi levels; semiconductors and insulators; electrons and holes in semiconductors; impurity effects; generation and recombination; mobility and other electrical properties of semiconductors; thermal and optical properties; p-n junctions; metal-semiconductor contacts.
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| | | (0-0-3) (Lec-Lab-Credit Hours)
This course introduces operating principles and develops models of modern semiconductor devices that are useful in the analysis and design of integrated circuits. Topics covered include: charge carrier transport in semiconductors; diffusion and drift, injection and lifetime of carriers; p-n junction devices; bipolar junction transistors; metal-oxide-semiconductor field effect transistors; metal-semiconductor field effect transistors and high electron mobility transistors; microwave devices; light emitting diodes, semiconductor lasers and photodetectors; integrated devices.
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| | (0-0-3) (Lec-Lab-Credit Hours)
Electronic optical and magnetic properties of materials
described in terms of modern physics. The processing and operation of
semiconductor and optoelecronic devices will be discussed and reliability
issues raised.
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| | (0-0-3) (Lec-Lab-Credit Hours)
Physical design of wireless communication systems, emphasizing present and next generation architectures. Impact of non-linear components on performance; noise sources and effects; interference; optimization of receiver and transmitter architectures; individual components (LNAs, power amplifiers, mixers, filters, VCOs, phase-locked loops, frequency synthesizers, etc.); digital signal processing for adaptable architectures; analog-digital converters; new component technologies (SiGe, MEMS, etc.); specifications of component performance; reconfigurability and the role of digital signal processing in future generation architectures; direct conversion; RF packaging; minimization of power dissipation in receivers.
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| | (0-0-3) (Lec-Lab-Credit Hours)
This course deals with the electrical, chemical, environmental and mechanical driving forces that compromise the integrity and lead to the failure of electronic materials and devices. Both chip and packaging level failures will be modeled physically and quantified statistically in terms of standard reliability mathematics. On the packaging level, thermal stresses, solder creep, fatigue and fracture, contact relaxation, corrosion and environmental degradation will be treated.
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| | (0-0-3) (Lec-Lab-Credit Hours)
Deals with aspects of the technology of processing procedures involved in the fabrication of microelectronic devices and microelectromechanical systems (MEMS). Students will become familiar with various fabrication techniques used for discrete devices, as well as large-scale integrated thin film circuits. Students will also learn that MEMS are sensors and actuators that are designed using different areas of engineering disciplines, and they are constructed using a microlithographically-based manufacturing process in conjunction with both semiconductor and micro-machining microfabrication technologies.
Prerequisites:
MT 507
(0-0-3)(Lec-Lab-Credit Hours)
An overview of microelectronics and photonics science and technology. It provides the student who wishes to specialize in their application, physics or fabrication with the necessary knowledge of how the different aspects are interrelated. It is taught in three modules: design and applications, taught by EE faculty; operation of electronic and photonic devices, taught by physics faculty; fabrication and reliability, taught by the materials faculty.
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| | (0-0-3) (Lec-Lab-Credit Hours)
Crystal structures, point defects, dislocations, slip systems, grain boundaries and microstructures. Scattering of X-rays and electrons; diffraction by single and polycrystalline materials and its application to material identification, crystal orientation, texture determination, strain measurement and crystal structure analysis.
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| | (0-0-3) (Lec-Lab-Credit Hours)
The goal of this course is to learn the basic concepts commonly utilized in the processing of advanced materials with specific compositions and microstructures. Solid state diffusion mechanisms are described with emphasis on the role of point defects, the mobility of diffusing atoms and their interactions. Macroscopic diffusion phenomena are analyzed by formulating partial differential equations and presenting their solutions. The relationships between processing and microstructure are developed on the basis of the rate of nucleation and growth processes that occur during condensation, solidification and precipitation. Diffusionless phase transformations observed in certain metallic and ceramic materials are discussed.
Prerequisites:
MT 603
(0-0-3)(Lec-Lab-Credit Hours)
The principal areas of concentration include a review of thermodynamic laws applying to closed systems, chemical potentials and equilibria in heterogeneous systems, fugacity and activity functions, solution thermodynamics, multicomponent metallic solutions, the thermodynamics of phase diagrams and phase transformations.
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| | (0-0-3) (Lec-Lab-Credit Hours)
The principal areas of concentration include a review of thermodynamic laws applying to closed systems, chemical potentials and equilibria in heterogeneous systems, fugacity and activity functions, solution thermodynamics, multicomponent metallic solutions, the thermodynamics of phase diagrams and phase transformations.
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| | (0-0-3) (Lec-Lab-Credit Hours)
The principal areas of concentration include a review of
thermodynamic laws applying to closed systems, chemical potentials and
equilibria in heterogeneous systems, fugacity and activity functions,
solution thermodynamics, multicomponent metallic solutions, the
thermodynamics of phase diagrams and phase transformations. Fall semester.
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| | (0-0-3) (Lec-Lab-Credit Hours)
Components for and design of optical communication systems; propagation of optical signals in single mode and multimode optical fibers; optical sources and photodetectors; optical modulators and multiplexers; optical communication systems: coherent modulators, optical fiber amplifiers and repeaters, transcontinental and transoceanic optical telecommunication system design; optical fiber local area networks.
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| | (0-0-3) (Lec-Lab-Credit Hours)
Selected topics in surface modification and coatings technology, such as chem-ical vapor deposition, physical vapor deposition, ion implantation or other. Description of the processing techniques, characterization and performance evaluation of the surfaces.
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| | (0-0-3) (Lec-Lab-Credit Hours)
Stress-strain relationships, theory of linear viscoelasticity and relaxation spectra, temperature dependence of viscoelastic behavior, dielectric properties, dynamic mechanical and electrical testing, molecular theories of flexible chains, statistical mechanics and thermodynamics of rubber-like undiluted systems, and morphology of high polymers.
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| | (0-0-3) (Lec-Lab-Credit Hours)
Physical design of wireless communication systems,
emphasizing present and next generation architectures. Impact of non-linear components on performance; noise sources and effects; interference; optimization of receiver and transmitter architectures; individual components (LNAs, power amplifiers, mixers, filters, VCOs, phase-locked loops, frequency synthesizers, etc.); digital signal processing for adaptable architectures; analog-digital
converters; new component technologies (SiGe, MEMS, etc.);
specifications of component performance; reconfigurability and the role of digital signal processing in future generation architectures; direct
conversion; RF packaging; minimization of power dissipation in receivers. Physical design of wireless communication systems,
emphasizing present and next generation architectures. Impact of non-linear components on performance; noise sources and effects; interference; optimization of receiver and transmitter architectures; individual components (LNAs, power amplifiers,
mixers, filters, VCOs, phase-locked loops, frequency
synthesizers, etc.); digital signal processing for adaptable architectures;
analog-digital converters; new component technologies (SiGe, MEMS, etc.); specifications of component performance; reconfigurability and the role of digital signal processing in future generation architectures; direct
conversion; RF packaging; minimization of power dissipation in receivers.
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| | (0-0-3) (Lec-Lab-Credit Hours)
This course introduces students to the principles and design techniques of very large scale integrated circuits (VLSI). Topics include: MOS transistor characteristics, DC analysis, resistance, capacitance models, transient analysis, propagation delay, power dissipation, CMOS logic design, transistor sizing, layout methodologies, clocking schemes, case studies. Students will use VLSI CAD tools for layout and simulation. Selected class projects may be sent for fabrication.
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| | (0-0-3) (Lec-Lab-Credit Hours)
Lectures by department faculty, guest speakers, and doctoral students on recent research. Enrollment during the entire period of study is required of all full-time students. No credit. Must be taken every semester.
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| | (0-0-3) (Lec-Lab-Credit Hours)
One to six credits. Limit of six credits for the degree of Master of Engineering.
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| | (0-0-3) (Lec-Lab-Credit Hours)
One to six credits. Limit of six credits for the degree of Doctor of Philosophy.
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| | (0-0-3) (Lec-Lab-Credit Hours)
A participating seminar on topics of current interest and
importance in Materials.
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| | (0-0-5) (Lec-Lab-Credit Hours)
Research for the degree of Master of Science or Master of Engineering.
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| | (0-0-3) (Lec-Lab-Credit Hours)
Original research leading to the doctoral dissertation.
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| | (3-0-3) (Lec-Lab-Credit Hours)
Description of simple physical models which account for electrical conductivity and thermal properties of solids. Basic crystal lattice structures, X-ray diffraction and dispersion curves for phonons and electrons in reciprocal space. Energy bands, Fermi surfaces, metals, insulators, semiconductors, superconductivity and ferromagnetism. Fall semester. Typical text: Kittel, Introduction to Solid State Physics.
Prerequisites:
PEP 242 Modern Physics
(3-0-3)(Lec-Lab-Credit Hours)
Simple harmonic motion, oscillations and pendulums; Fourier analysis; wave properties; wave-particle dualism; the Schrödinger equation and its interpretation; wave functions; the Heisenberg uncertainty principle; quantum mechanical tunneling and application; quantum mechanics of a particle in a "box," the hydrogen atom; electronic spin; properties of many electron atoms; atomic spectra; principles of lasers and applications; electrons in solids; conductors and semiconductors; the n-p junction and the transistor; properties of atomic nuclei; radioactivity; fusion and fission. Spring Semester.
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Electromagnetism
(3-0-3)(Lec-Lab-Credit Hours)
Electrostatics; Coulomb-Gauss law; Poisson-Laplace equations; boundary value problems; image techniques;dielectric media; magnetostatics; multipole expansion; electromagnetic energy; electromagnetic induction; Maxwell’s equations; electromagnetic waves, radiation, waves in bounded regions, wave equations and retarded solutions; simple dipole antenna radiation theory; transformation law of electromagnetic fields. Spring semester. Typical text: Reitz, Milford and Christy, Foundation of Electromagnetic Theory.
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| | (3-0-3) (Lec-Lab-Credit Hours)
Lectures, demonstrations and laboratory experiments, selected from among the following topics, depending on student interest: vacuum technology; thin-film preparation; scanning electron microscopy; infrared spectroscopy, ellipsometry: electron spectroscopies-Auger,
photoelectron, LEED; ion spectroscopies SIMS, IBS, field emission; surface
properties-area, roughness, and surface tension.
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| | (3-0-3) (Lec-Lab-Credit Hours)
This course is an introduction to quantum mechanics for students in physics and engineering. Techniques discussed include solutions of the Schrodinger equation in one and three dimensions, and operator and matrix methods. Applications include infinite and finite quantum wells, barrier penetration and scattering in one dimension, the harmonic oscillator, angular momentum, central force problems, including the hydrogen atom, and spin. Fall semester. Typical text: Quantum Physics by Gasiorowicz
Prerequisites:
MA 221 Differential Equations
(4-0-4)(Lec-Lab-Credit Hours)
Ordinary differential equations of first and second order, homogeneous and non-homogeneous equations; improper integrals, Laplace transforms; review of infinite series, series solutions of ordinary differential equations near an ordinary point; boundary-value problems; orthogonal functions; Fourier series; separation of variables for partial differential equations.
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Modern Physics
(3-0-3)(Lec-Lab-Credit Hours)
Simple harmonic motion, oscillations and pendulums; Fourier analysis; wave properties; wave-particle dualism; the Schrödinger equation and its interpretation; wave functions; the Heisenberg uncertainty principle; quantum mechanical tunneling and application; quantum mechanics of a particle in a "box," the hydrogen atom; electronic spin; properties of many electron atoms; atomic spectra; principles of lasers and applications; electrons in solids; conductors and semiconductors; the n-p junction and the transistor; properties of atomic nuclei; radioactivity; fusion and fission. Spring Semester.
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| | (3-0-3) (Lec-Lab-Credit Hours)
This course is meant as the first in a two-course sequence on non-relativistic quantum mechanics for physics graduate students, with an emphasis on applications to atomic, molecular, and solid state physics. Undergraduate students may take this course as a Technical Elective. Topics covered include: review of Schrödinger wave mechanics; operator algebra, theory of representation, and matrix mechanics; symmetries in quantum mechanics; spin and formal theory of angular momentum, including addition of angular momentum; and approximation methods for stationary problems, including time independent perturbation theory, WKB approximation, and variational methods. Typical text: Quantum Mechanics by E. Merzbacher.
Prerequisites:
PEP 532 PEP 538 Introduction to Mechanics
(3-0-3)(Lec-Lab-Credit Hours)
Particle motion in one dimension. Simple harmonic oscillators. Motion in two and three dimensions, kinematics, work and energy, conservative forces, central forces, and scattering. Systems of particles, linear and angular momentum theorems, collisions, linear spring systems, and normal modes. Lagrange’s equations and applications to simple systems. Introduction to moment of inertia tensor and to Hamilton’s equations.
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Quantum Mechanics and Engineering Applications
(3-0-3)(Lec-Lab-Credit Hours)
This course is meant to serve as an introduction to formal quantum mechanics as well as to apply the basic formalism to several generic and important applications.
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Kinetic theory: ideal gases, distribution functions, Maxwell-Boltzmann distribution, Boltzmann equation, H-theorem and entropy, and simple transport theory. Thermodynamics: review of first and second laws, thermodynamic potentials, Legendre transformation, and phase transitions. Elementary statistical mechanics: introduction to microcanonical, canonical, and grand canonical distributions, partition functions, simple applications, including ideal Maxwell-Boltzmann, Einstein-Bose, and Fermi-Dirac gases, paramagnetic systems, and blackbody radiation. Typical text: Reif, Statistical and Thermal Physics. Fall semester.
Prerequisites:
MA 221 Differential Equations
(4-0-4)(Lec-Lab-Credit Hours)
Ordinary differential equations of first and second order, homogeneous and non-homogeneous equations; improper integrals, Laplace transforms; review of infinite series, series solutions of ordinary differential equations near an ordinary point; boundary-value problems; orthogonal functions; Fourier series; separation of variables for partial differential equations.
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Modern Physics
(3-0-3)(Lec-Lab-Credit Hours)
Simple harmonic motion, oscillations and pendulums; Fourier analysis; wave properties; wave-particle dualism; the Schrödinger equation and its interpretation; wave functions; the Heisenberg uncertainty principle; quantum mechanical tunneling and application; quantum mechanics of a particle in a "box," the hydrogen atom; electronic spin; properties of many electron atoms; atomic spectra; principles of lasers and applications; electrons in solids; conductors and semiconductors; the n-p junction and the transistor; properties of atomic nuclei; radioactivity; fusion and fission. Spring Semester.
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| | (3-0-3) (Lec-Lab-Credit Hours)
Principles of environmental reactions with emphasis on aquatic chemistry; reaction and phase equilibria; acid-base and carbonate systems; oxidation-reduction; colloids; organic contaminants classes, sources, and fates; groundwater chemistry; and atmospheric chemistry.
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| | (3-0-3) (Lec-Lab-Credit Hours)
A study of the chemical and physical operation involved in treatment of potable water, industrial process water, and wastewater effluent; topics include chemical precipitation, coagulation, flocculation, sedimentation, filtration, disinfection, ion exchange, oxidation, adsorption, flotation, and membrane processes. A physical-chemical treatment plant design project is an integral part of the course. The approach of unit operations and unit processes is stressed.
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| | (3-0-3) (Lec-Lab-Credit Hours)
Deals with aspects of the technology of processing procedures involved in the fabrication of microelectronic devices and microelectromechanical systems (MEMS). Students will become familiar with various fabrication techniques used for discrete devices as well as large-scale integrated thin-film circuits. Students will also learn that MEMS are sensors and actuators that are designed using different areas of engineering disciplines and they are constructed using a microlithographically-based manufacturing process in conjunction with both semiconductor and micromachining microfabrication technologies
Prerequisites:
PEP 507 Introduction to Microelectronics and Photonics
(3-0-3)(Lec-Lab-Credit Hours)
An overview of Microelectronics and Photonics Science and Technology. It provides the student who wishes to specialize in the application, physics or fabrication with the necessary knowledge of how the different aspects are interrelated. It is taught in three modules: design and applications, taught by EE faculty; operation of electronic and photonic devices, taught by Physics faculty; fabrication and reliability, taught by the
Materials faculty.
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| | (3-0-3) (Lec-Lab-Credit Hours)
This course deals with the fundamentals and applications of nanoscience and nanotechnology. Size-dependent phenomena, ways and means of designing and synthesizing nanostructures, and cutting-edging applications will be presented in an integrated and interdisciplinary manner.
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| | (3-0-3) (Lec-Lab-Credit Hours)
The goal of this course is to learn the basic concepts commonly utilized in the processing of advanced materials with specific compositions and microstructures. Solid state diffusion mechanisms are described with emphasis on the role of point defects, the mobility of diffusing atoms, and their interactions. Macroscopic diffusion phenomena are analyzed by formulating partial differential equations and presenting their solutions. The relationships between processing and microstructure are developed on the basis of the rate of nucleation and growth processes that occur during condensation, solidification, and precipitation. Diffusionless phase transformations observed in certain metallic and ceramic materials are discussed.
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| | (3-0-3) (Lec-Lab-Credit Hours)
This course covers the environmental and health aspects of nanotechnology. It presents an overview of nanotechnology along with characterization and properties of nanomaterials. The course material covers the biotoxicity and ecotoxicity of nanomaterials. A sizable part of the course is devoted to discussions about the application of nanotechnology for environmental remediation along with discussions about fate and transport of nanomaterials. Special emphasis is given to risk assessment and risk management of nanomaterials, ethical and legal aspects of nanotechnology, and nano-industry and nano-entrepreneurship.
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| | (3-0-3) (Lec-Lab-Credit Hours)
This course provides an overview and industrial perspectives regarding downstream separation in drug substance development and manufacturing. Basic principles and practical applications of unit operations most commonly employed in the pharmaceutical industry will be discussed, including extraction, absorption, membrane, distillation, crystallization, filtration, and drying. Examples will be discussed to illustrate the intrinsic relationship between process development, equipment selection, and scale-up success.
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| | (3-0-3) (Lec-Lab-Credit Hours)
Lectures, demonstrations, and laboratory experiments, selected from among the following topics, depending on student interest: vacuum technology; thin-film preparation; scanning electron microscopy; infrared spectroscopy and ellipsometry; electron spectroscopy; Auger, photoelectron, and LEED; ion spectroscopies; SIMS, IBS, and field emission; surface properties-area, roughness, and surface tension.
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| | (3-0-3) (Lec-Lab-Credit Hours)
Upon completion of this course, students will be able to demonstrate an understanding of the major classes of engineering materials, their principal properties, and design requirements that serve as both the basis for materials selection, as well as for the ongoing development of new materials. This course is substantially differentiated from introductory materials courses by its very specific focus on materials whose use puts them in direct contact with physiological systems. Thus, the course begins with brief sections on inflammatory response, thrombosis, infection, and device failure. It then concentrates on developing the fundamental materials science and engineering concepts underlying the structure-property relationships in both synthetic and natural polymers, metals and alloys, and ceramics relevant to in vivo medical device technology.
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| | (3-0-3) (Lec-Lab-Credit Hours)
This course follows the introductory course and covers advanced topics in the design, modeling, and fabrication of micro and nano electromechanical systems. The materials will be broad and multidisciplinary including: review of micro and nano electromechanical systems, dimensional analysis and scaling, thermal, transport, fluids, microelectronics, feedback control, noise, and electromagnetism at the micro and nanoscales; the modeling of a variety of new MEMS/NEMS devices; and alternative approaches to the continuum mechanics theory. The goal will be achieved through a combination of lectures, case studies, individual homework assignments, and design projects carried out in teams.
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| | | (3-0-3) (Lec-Lab-Credit Hours)
The course covers recent advances in macromolecular science, including polyelectrolytes and water-soluble polymers, synthetic and biological macromolecules at surfaces, self-assembly of synthetic and biological macromolecules, and polymers for biomedical applications.
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| | (3-0-3) (Lec-Lab-Credit Hours)
Topics at the interface of polymer chemistry and biomedical sciences, focusing on areas where polymers have made a particularly strong contribution, such as in biomedical sciences and pharmaceuticals. Synthesis and properties of biopolymers; biomaterials; nanotechnology smart polymers; functional applications in biotechnology, tissue and cell engineering; and biosensors and drug delivery.
Prerequisites:
CH 244
(3-0-3)(Lec-Lab-Credit Hours)
Continuation of CH 243; reactions of aromatic compounds; infrared and nuclear magnetic resonance spectroscopy.
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| | (3-0-3) (Lec-Lab-Credit Hours)
This course will provide a comprehensive introduction to the rapidly developing field of nanomedicine and discuss the application of nanoscience and nanotechnology in medicine such as, in diagnosis, imaging and therapy, surgery, and drug delivery.
Prerequisites:
NANO 600
(3-0-3)(Lec-Lab-Credit Hours)
This course deals with the fundamentals and applications of nanoscience and nanotechnology. Size-dependent phenomena, ways and means of designing and synthesizing nanostructures, and cutting-edging applications will be presented in an integrated and interdisciplinary manner.
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| | (3-0-3) (Lec-Lab-Credit Hours)
As an introduction to micro/nano fluidics, course topics include basic fluid mechanical theories, experimental techniques, fabrication techniques and applications of micro/nano fluidics. The theory part will cover continuum fluid mechanics at micro/nano scales, molecular approaches, capillary effects, electrokinetic flows, acoustofluidics and optofluidics. The experimental part will cover micro/nano rheology and particle image velocimetry. The fabrication part will cover materials and machining techniques for micro/nano fluidic devices. The application part will cover micro/nano fluidic devices for flow control, life sciences and chemistry. As a term project, individual students are required to perform a case study for their own selected topic in micro/nano fluidics, to conduct a literature survey/summary and to propose/analyze their own new design idea of a micro/nano fluidic devices by utilizing the knowledge obtained throughout the course.
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| | (3-0-3) (Lec-Lab-Credit Hours)
A survey course covering the chemical, biological and material science aspects of interfacial phenomena. Applications to adhesion, biomembranes, colloidal stability, detergency, lubrication, coatings, fibers and powders - where surface properties play an important role.
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| | (3-0-3) (Lec-Lab-Credit Hours)
This course describes the application of nano- and micro-fabrication methods to build tools for exploring the mysteries of biological systems. It is a graduate-level course that will cover the basics of biology and the principles and practice of nano- and microfabrication techniques, with a focus on applications in biomedical and biological research.
Prerequisites:
NANO 600
(3-0-3)(Lec-Lab-Credit Hours)
This course deals with the fundamentals and applications of nanoscience and nanotechnology. Size-dependent phenomena, ways and means of designing and synthesizing nanostructures, and cutting-edging applications will be presented in an integrated and interdisciplinary manner.
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| | (3-0-3) (Lec-Lab-Credit Hours)
This advanced course covers the mechanism and biological role of signal transduction in mammalian cells. Topics included are extracellular regulatory signals, intracellular signal transduction pathways, role of tissue context in the function of cellular regulation, and examples of biological processes controlled by specific cellular signal transduction pathways.
Prerequisites:
CH 381
(3-3-4)(Lec-Lab-Credit Hours)
The structure and function of the cell and its subcellular organelles is studied. Biological macromolecules, enzymes, biomembranes, biological transport, bioenergetics, DNA replication, protein synthesis and secretion, motility, and cancer are covered. Cell biology experiments and interactive computer simulation exercises are conducted in the laboratory.
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(3-3-4)(Lec-Lab-Credit Hours)
Introduction to the study of molecular basis of inheritance. Starts with classical Mendelian genetics and proceeds to the study and function of DNA, gene expression and regulation in prokaryotes and eukaryotes, genome dynamics and the role of genes in development, and cancer. All topics include discussions of current research advances. Accompanied by laboratory section that explores the lecture topics in standard wet laboratory experiments and in computer simulations.
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| | (3-0-3) (Lec-Lab-Credit Hours)
This course is intended to introduce the concept of electronic energy band engineering for device applications. Topics to be covered are electronic energy bands, optical properties, electrical transport properties of multiple quantum wells, superlattices, quantum wires, and quantum dots; mesoscopic systems, applications of such structures in various solid state devices, such as high electron mobility, resonant tunneling diodes, and other negative differential conductance devices, double-heterojunction injection lasers, superlattice-based infrared detectors, electron-wave devices (wave guides, couplers, switching devices), and other novel concepts and ideas made possible by nano-fabrication technology. Fall semester. Typical text: M. Jaros, Physics and Applications of Semiconductor Microstructures; G. Bastard, Wave Mechanics Applied to Semiconductor Heterostructures.
Prerequisites:
PEP 503
(3-0-3)(Lec-Lab-Credit Hours)
Description of simple physical models which account for electrical conductivity and thermal properties of solids. Basic crystal lattice structures, X-ray diffraction and dispersion curves for phonons and electrons in reciprocal space. Energy bands, Fermi surfaces, metals, insulators, semiconductors, superconductivity and ferromagnetism. Fall semester. Typical text: Kittel, Introduction to Solid State Physics.
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(3-0-3)(Lec-Lab-Credit Hours)
This course is meant to serve as an introduction to formal quantum mechanics as well as to apply the basic formalism to several generic and important applications.
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This course deals with the principles of light interactions with biological and biomedical-relevant systems. The enabling aspects of nanotechnology for advanced biosensing, medical diagnosis, and therapeutic treatment will be discussed.
Prerequisites:
NANO 600
(3-0-3)(Lec-Lab-Credit Hours)
This course deals with the fundamentals and applications of nanoscience and nanotechnology. Size-dependent phenomena, ways and means of designing and synthesizing nanostructures, and cutting-edging applications will be presented in an integrated and interdisciplinary manner.
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Lectures by department faculty, guest speakers and doctoral students on recent research.
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This graduate course will introduce the applications of multiscale theory and computational techniques in the fields of materials and mechanics. Students will obtain fundamental knowledge on homogenization and heterogeneous materials, and be exposed to various sequential and concurrent multiscale techniques. The first half of the course will be focused on the homogenization theory and its applications in heterogeneous materials. In the second half multiscale computational techniques will be addressed through multiscale finite element methods and atomistic/continuum computing. Students are expected to develop their own course projects based on their research interests and the relevant topics learned from the course.
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Progress in the technology of nanostructure growth; space and time scales; quantum confined systems; quantum wells, coupled wells, and superlattices; quantum wires and quantum dots; electronic states; magnetic field effects; electron-phonon interaction; and quantum transport in nanostructures: Kubo formalism and Butikker-Landau formalism; spectroscopy of quantum dots; Coulomb blockade, coupled dots, and artificial molecules; weal localization; universal conductance fluctuations; phase-breaking time; theory of open quantum systems: fluctuation-dissipation theorem; and applications to quantum transport in nanostructures.
Prerequisites:
PEP 554
(3-0-3)(Lec-Lab-Credit Hours)
Basic concepts of quantum mechanics, states, operators; time development of Schrödinger and Heisenberg pictures; representation theory; symmetries; perturbation theory; systems of identical particles, L-S and j-j coupling; fine and hyperfine structure; scattering theory; molecular structure. Spring semester. Typical texts: Gottfried, Quantum Mechanics, Schiff, Quantum Mechanics.
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(3-0-3)(Lec-Lab-Credit Hours)
Crystal symmetry. Space-group-theory analysis of normal modes of lattice vibration, phonon dispersion relations, and Raman and infrared activity. Crystal field splitting of ion energy level and transition selection rules. Bloch theorem and calculation of electronic energy bands through tight binding and pseudopotential methods for metals and semiconductors and Fermi surfaces. Transport theory, electrical conduction, thermal properties, cyclotron resonance, de Haas van Alfen, and Hall effects. Dia-, para-, and ferro-magnetism and magnon spinwaves. Spring semester. Typical texts: Callaway, Quantum Theory of Solid State; Ashcroft and Mermin, Solid State Physics; and Kittel, Quantum Theory of Solids.
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| Pharmaceutical Process Engineering |
| | (3-0-3) (Lec-Lab-Credit Hours)
This course provides an overview and industrial perspectives regarding downstream separation in drug substance development and manufacturing. Basic principles and practical applications of unit operations most commonly employed in the pharmaceutical industry will be discussed, including extraction, absorption, membrane, distillation, crystallization, filtration, and drying. Examples will be discussed to illustrate the intrinsic relationship between process development, equipment selection, and scale up success.
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| | (3-0-3) (Lec-Lab-Credit Hours)
Fundamentals of mixing relevant to pharmaceutical engineering, flow patterns, dead zones, components of mixers, importance of baffling, determination of flow, power, and shear rates, effect of rheology, “shaken, not stirred”, why viscosity affects more than just Reynolds numbers, continuous processing, heat transfer, suspending solids that sink or float, wetting out solids, concepts of crystallization, catalysis, mass transfer, liquid-liquid dispersions, emulsions, and separations, fermenters, hydrogenators, other gas-liquid applications, pit-falls of scale-up, why scale down is the better way to design, process intensification and solids-solids mixing.
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| | | (3-0-3) (Lec-Lab-Credit Hours)
This course is aimed at the application of advanced process control techniques in industry with a focus on pharmaceutical, petrochemical and power distribution applications. Topics considered include: reactor and system modeling; data collection for data regression and predictive control modeling for control systems design and operations decision support are discussed and demonstrated. State and parameter estimation techniques, optimization of reactor productivity for batch, fed-batch and continuous operations and expert systems approaches to monitoring and control are taught using standard control system programming languages. Distribution of control application functions is discussed. An overview of a complete automation project - from design to startup - of a pharmaceutical plant will be discussed.
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| | (3-0-3) (Lec-Lab-Credit Hours)
This course will provide a fundamental understanding, and the application of emerging and current approaches to reaction engineering and catalysis in the pharmaceutical and fine chemical industries. The course will focus on promising technologies such as enzymatic catalysis and bioreactor design, chiral synthesis and kinetics, multiphase reactions, and microreactor technology with emphasis throughout on industrially relevant reactions.
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Chemical Engineering & Materials Science Department
Henry Du, Director |
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